Peninsula Medical School: Recent submissions
Now showing items 141-150 of 1220
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Continuous Subcutaneous Foslevodopa/Foscarbidopa in Parkinson’s Disease: Safety and Efficacy Results From a 12-Month, Single-Arm, Open-Label, Phase 3 Study
(Springer Science and Business Media LLCNew Zealand, 2023-08-26)Introduction Foslevodopa/foscarbidopa, a soluble formulation of levodopa/carbidopa (LD/CD) prodrugs for the treatment of Parkinson’s disease (PD), is administered as a 24-hour/day continuous subcutaneous infusion (CSCI) ... -
Early computed tomography coronary angiography and preventative treatment in patients with suspected acute coronary syndrome: A secondary analysis of the RAPID-CTCA trial
(Elsevier BVUnited States, 2023-12)Background Computed tomography coronary angiography (CTCA) offers detailed assessment of the presence of coronary atherosclerosis and helps guide patient management. We investigated influences of early CTCA on the subsequent ... -
Quality standards for the management of alcohol-related liver disease: consensus recommendations from the British Association for the Study of the Liver and British Society of Gastroenterology ARLD special interest group
(BMJEngland, 2023-10)Objective Alcohol-related liver disease (ALD) is the most common cause of liver-related ill health and liver-related deaths in the UK, and deaths from ALD have doubled in the last decade. The management of ALD requires ... -
Health promotion and public health
(RCN Publishing (RCNi)England, 2023-07-27) -
Treatment of age‐related macular degeneration with aflibercept using a treat, extend and fixed protocol; A 4‐year study of treatment outcomes, durability, safety and quality of life (An extension to the <scp>MATE</scp> randomised controlled trial)
(WileyEngland, 2023-09-30)<jats:title>Abstract</jats:title><jats:sec><jats:title>Purpose</jats:title><jats:p>Data are limited pertaining to the long‐term benefits of aflibercept treatment for neovascular age‐related macular degeneration (nAMD). ... -
Gelation of cytoplasmic expanded CAG RNA repeats suppresses global protein synthesis
(Springer Science and Business Media LLCUnited States, 2023-11)RNA molecules with the expanded CAG repeat (eCAGr) may undergo sol–gel phase transitions, but the functional impact of RNA gelation is completely unknown. Here, we demonstrate that the eCAGr RNA may form cytoplasmic ... -
Effectiveness of out-patient based acute heart failure care: a pilot randomised controlled trial
(Informa UK LimitedEngland, 2023-10-03)Objectives Acute heart failure (AHF) hospitalisation is associated with 10% mortality. Outpatient based management (OPM) of AHF appeared effective in observational studies. We conducted a pilot randomised controlled trial ... -
Protocol for the feasibility and implementation study of a model of best practice in primary care led postdiagnostic dementia care: PriDem
(BMJEngland, 2023-08)Introduction Care is often inadequate and poorly integrated after a dementia diagnosis. Research and policy highlight the unaffordability and unsustainability of specialist-led support, and instead suggest a task-shared ...
