Peninsula Medical School: Recent submissions
Now showing items 91-100 of 1220
-
Preoperative aerobic fitness and perioperative outcomes in patients undergoing cystectomy before and after implementation of a national lockdown
(Elsevier BVEngland, 2024-03)Abstract Background Lower fitness is a predictor of adverse outcomes after radical cystectomy. Lockdown measures during the COVID-19 pandemic affected daily physical activity. We hypothesised that lockdown during the ... -
Embedding Patient Input in Outcome Measures for Long‐Term Disease‐Modifying Parkinson Disease Trials
(WileyUnited States, 2023-12-22)Background Clinical trials of disease-modifying therapies in PD require valid and responsive primary outcome measures that are relevant to patients. Objectives The objective is to select a patient-centered primary outcome ... -
Patient safety in remote primary care encounters: multimethod qualitative study combining Safety I and Safety II analysis
(BMJEngland, 2023-11-28)Abstract Background Triage and clinical consultations increasingly occur remotely. We aimed to learn why safety incidents occur in remote encounters and how to prevent them. Setting and sample UK primary care. 95 safety ... -
Training needs for staff providing remote services in general practice: a mixed-methods study
(Royal College of General PractitionersEngland, 2024-01)Abstract Background Contemporary general practice includes many kinds of remote encounter. The rise in telephone, video and online modalities for triage and clinical care requires clinicians and support staff to be trained, ... -
Fast-track extubation after orthotopic liver transplant associates with reduced incidence of acute kidney injury and renal replacement therapy: A propensity-matched analysis
(Elsevier BV, 2023-02)Introduction Liver transplantation is the only available definitive treatment for end-stage liver disease and subtypes of hepatocellular carcinoma. Patient outcomes have significantly improved alongside developments in ... -
Four System Enablers of Large‐System Transformation in Health Care: A Mixed Methods Realist Evaluation
(WileyUnited States, 2023-12-25)Abstract Policy Points The implementation of large-scale health care interventions relies on a shared vision, commitment to change, coordination across sites, and a spanning of siloed knowledge. Enablers of the system ... -
Incorporating usability evaluation into iterative development of an online platform to support research participation in Parkinson’s disease: a mixed methods protocol
(BMJEngland, 2023-12)Abstract Introduction Many people with Parkinson’s (PwP) are not given the opportunity or do not have adequate access to participate in clinical research. To address this, we have codeveloped with users an online platform ... -
Improved structure and function in early detected second eye neovascular age-related macular degeneration; FASBAT/EDNA report 1
(Elsevier BVUnited States, 2024-01-01)Abstract Purpose Visual Acuity (VA) and structural biomarker assessment before and at 24-months after early detection and routine treatment of second eye involvement with neovascular age-related macular degeneration (nAMD) ... -
A novel patient-derived meningioma spheroid model as a tool to study and treat epithelial-to-mesenchymal transition (EMT) in meningiomas
(Springer Science and Business Media LLCEngland, 2023-12-15)Meningiomas are the most common intracranial brain tumours. These tumours are heterogeneous and encompass a wide spectrum of clinical aggressivity. Treatment options are limited to surgery and radiotherapy and have a risk ... -
Ribogenesis boosts controlled by HEATR1-MYC interplay promote transition into brain tumour growth
(Springer Science and Business Media LLCEngland, 2024-01-15)<jats:title>Abstract</jats:title><jats:p>Cell commitment to tumourigenesis and the onset of uncontrolled growth are critical determinants in cancer development but the early events directing tumour initiating cell (TIC) ...
