Peninsula Medical School: Recent submissions
Now showing items 61-70 of 1220
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Mitogen-Activated Protein Kinase Cross-Talk Interaction Modulates the Production of Melanins in Aspergillus fumigatus
(American Society for MicrobiologyUnited States, 2019-04-30)<jats:p> <jats:named-content content-type="genus-species">Aspergillus fumigatus</jats:named-content> is the most important airborne human pathogenic fungus, causing thousands of deaths per year. ... -
The low affinity glucose transporter HxtB is also involved in glucose signalling and metabolism in Aspergillus nidulans
(Springer Science and Business Media LLCEngland, 2017)<jats:title>Abstract</jats:title><jats:p>One of the drawbacks during second-generation biofuel production from plant lignocellulosic biomass is the accumulation of glucose, the preferred carbon source of microorganisms, ... -
Protein Kinase A and High-Osmolarity Glycerol Response Pathways Cooperatively Control Cell Wall Carbohydrate Mobilization in <i>Aspergillus fumigatus</i>
(American Society for MicrobiologyUnited States, 2018-12-21)<jats:p> <jats:named-content content-type="genus-species">Aspergillus fumigatus</jats:named-content> is an opportunistic human pathogen causing allergic reactions or systemic infections such as ... -
Comprehensive Analysis of Aspergillus nidulans PKA Phosphorylome Identifies a Novel Mode of CreA Regulation
(American Society for MicrobiologyUnited States, 2019-04-30)<jats:p>The cyclic AMP (cAMP)-dependent protein kinase A (PKA) signaling pathway is well conserved across eukaryotes, and previous work has shown that it plays an important role in regulating development, growth, and ... -
Aspergillus fumigatus High Osmolarity Glycerol Mitogen Activated Protein Kinases SakA and MpkC Physically Interact During Osmotic and Cell Wall Stresses
(Frontiers Media SASwitzerland, 2019)Aspergillus fumigatus, a saprophytic filamentous fungus, is a serious opportunistic pathogen of mammals and it is the primary causal agent of invasive aspergillosis (IA). Mitogen activated protein Kinases (MAPKs) are ... -
Carbon Catabolite Repression in Filamentous Fungi Is Regulated by Phosphorylation of the Transcription Factor CreA
(American Society for MicrobiologyUnited States, 2021-02-23)<jats:p> In filamentous fungi, the transcription factor CreA controls carbohydrate metabolism through the regulation of genes encoding enzymes required for the use of alternative carbon sources. In this work, ... -
A CO <sub>2</sub> sensing module modulates β-1,3-glucan exposure in <i>Candida albicans</i>
(American Society for MicrobiologyUnited States, 2024-02-14)<jats:p> Our innate immune defenses have evolved to protect us against microbial infection in part via receptor-mediated detection of “pathogen-associated molecular patterns” (PAMPs) expressed by invading ... -
Anticipatory Stress Responses and Immune Evasion in Fungal Pathogens
(Elsevier BVEngland, 2021-05)In certain niches, microbes encounter environmental challenges that are temporally linked. In such cases, microbial fitness is enhanced by the evolution of anticipatory responses where the initial challenge simultaneously ... -
The <i>Aspergillus nidulans</i> Pyruvate Dehydrogenase Kinases Are Essential To Integrate Carbon Source Metabolism
(Oxford University Press (OUP)England, 2018-07-01)<jats:title>Abstract</jats:title> <jats:p>The pyruvate dehydrogenase complex (PDH), that converts pyruvate to acetyl-coA, is regulated by pyruvate dehydrogenase kinases (PDHK) and phosphatases (PDHP) that ... -
Aspergillus nidulans protein kinase A plays an important role in cellulase production
(Springer Science and Business Media LLCEngland, 2015-12)BACKGROUND: The production of bioethanol from lignocellulosic feedstocks is dependent on lignocellulosic biomass degradation by hydrolytic enzymes. The main component of lignocellulose is cellulose and different types of ...
