Peninsula Medical School: Recent submissions
Now showing items 51-60 of 1220
-
Diabetic peripheral neuropathy: advances in diagnosis and strategies for screening and early intervention
(Elsevier BVEngland, 2019-12)Diabetic peripheral neuropathy (DPN) is a common complication of both type 1 and 2 diabetes. It is a leading cause of lower-limb amputation and disabling neuropathic pain. Amputations in patients with diabetes have a ... -
Sociodemographic and Health Factors Affecting Uptake of Second Dose Covid-19 Vaccine in England: Retrospective Cohort Study Using Data from the National Primary Care Sentinel Surveillance Network (Oxford-Royal College of General Practitioners Clinical Informatics Digital Hub)
(Elsevier BV, 2022)Background: Two doses of COVID-19 vaccine offer greater protection than one dose. There are known disparities in COVID-19 outcomes and vaccine uptake. However, it is not known whether non-uptake of the second dose in ... -
COVID-19 vaccine effectiveness against hospitalisation and death of people in clinical risk groups during the Delta variant period: English primary care network cohort study
(Elsevier BVEngland, 2023-10)BACKGROUND: COVID-19 vaccines have been shown to be highly effective against hospitalisation and death following COVID-19 infection. COVID-19 vaccine effectiveness estimates against severe endpoints among individuals with ... -
Development of a modified Cambridge Multimorbidity Score for use with SNOMED CT: an observational English primary care sentinel network study
(Royal College of General PractitionersEngland, 2023-06)<jats:sec><jats:title>Background</jats:title><jats:p>People with multiple health conditions are more likely to have poorer health outcomes and greater care and service needs; a reliable measure of multimorbidity would ... -
Trends in direct oral anticoagulant (DOAC) prescribing in English primary care (2014–2019)
(BMJEngland, 2023-02)<jats:sec><jats:title>Background</jats:title><jats:p>In England, most prescribing of direct-acting oral anticoagulants for atrial fibrillation (AF) is in primary care. However, there remain gaps in our understanding of ... -
Relationship of cardiorenal risk factors with albuminuria based on age, smoking, glycaemic status and BMI: a retrospective cohort study of the UK Biobank data
(BMJ, 2023-11)<jats:sec><jats:title>Introduction</jats:title><jats:p>Smoking is harmful, and its cessation is recommended to prevent chronic kidney disease, which often begins with abnormal leakage of albumin in the urine, called ... -
Nature of β-1,3-Glucan-Exposing Features on Candida albicans Cell Wall and Their Modulation
(American Society for MicrobiologyUnited States, 2022-12-20)<jats:p>Microbes that coexist with humans have evolved ways of avoiding or evading our immunological defenses. These include the masking by these microbes of their “pathogen-associated molecular patterns” (PAMPs), which ... -
The High Osmolarity Glycerol Mitogen-Activated Protein Kinase regulates glucose catabolite repression in filamentous fungi
(Public Library of Science (PLoS)United States, 2020)The utilization of different carbon sources in filamentous fungi underlies a complex regulatory network governed by signaling events of different protein kinase pathways, including the high osmolarity glycerol (HOG) and ... -
Mitogen activated protein kinases (MAPK) and protein phosphatases are involved in Aspergillus fumigatus adhesion and biofilm formation
(Elsevier BVNetherlands, 2018-03)The main characteristic of biofilm formation is extracellular matrix (ECM) production. The cells within the biofilm are surrounded by ECM which provides structural integrity and protection. During an infection, this ...